KMID : 0352720180420010001
|
|
Journal of Ginseng Research 2018 Volume.42 No. 1 p.1 ~ p.8
|
|
Ginseng and obesity
|
|
Li Zhipeng
Ji Geun-Eog
|
|
Abstract
|
|
|
Although ginseng has been shown to have an antiobesity effect, antiobesity-related mechanisms are complex and have not been completely elucidated. In the present study, we evaluated ginseng¡¯s effects on food intake, the digestion, and absorption systems, as well as liver, adipose tissue, and skeletal muscle in order to identify the mechanisms involved. A review of previous in vitro and in vivo studies revealed that ginseng and ginsenosides can increase energy expenditure by stimulating the adenosine monophosphate-activated kinase pathway and can reduce energy intake. Moreover, in high fat diet-induced obese and diabetic individuals, ginseng has shown a two-way adjustment effect on adipogenesis. Nevertheless, most of the previous studies into antiobesity effects of ginseng have been animal based, and there is a paucity of evidence supporting the suggestion that ginseng can exert an antiobesity effect in humans.
|
|
KEYWORD
|
|
AMPK, ginseng, ginsenoside, lipid metabolism, obesity
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|